Consists of a transcript which has been corrected by Pybus on several occasions. The content concerns causes of cancer, previous research and discovery dating from 1775.

Correspondence regarding Pybus' discharge from medical care and him disputing his demobilisation on medical grounds in 1918. In addition to this there is a classification of wounds sheet focusing on gun shots and also a Territorial Force Royal Army Medical Corps and memorandum of information for officers with information on allowances.

This file is labelled "The Towers School, Saltburn-by-the-Sea", most correspondence is to Pybus' elder sister Ivy, this includes the earlier correspondence. Some of the correspondence is to women who potentially worked in the school or were related to the Pybus family. Newsletters for the Queen Victoria High School Old Girls Association are included.

Letters regarding appointments and referrals from colleagues and discussion of cases, these usually have notes on the case or other cases written on the back, there are some specific case notes and surgery lists, x-ray films are included for some cases.

Letters regarding appointments and referrals from colleagues, patients updating Pybus and sending payments and discussion of cases, these usually have notes on the case or other cases written on the back.

Correspondence regarding reprints sent to Dr Shapiro and some general discussion about this, prevention of cancer and the possibility of a clean air campaign.

Correspondence regarding the British Medical Journal.

Letter regarding the Annual Representatives Meeting (the agenda is attached).

Letters regarding the newspaper clipping attached "Defume" (Diesel Exhaust Fume Abatement Society), Pybus refers Colwyn to the Clean Air Society. Colwyn's reply mentions Sir Walter Fergusson-Hannay.