The papers of Walter Runciman, 1st Viscount Runciman of Doxford (1870-1949), relate chiefly to his political career, but also include material concerning his personal and professional life. They cover his election campaigns and his political career, during the years 1894-1938, and in particular they cover the different political offices he held, as a Liberal M.P. and Cabinet Minister, and as a member of the Board of Education, 1908-11, and the Board of Trade, 1914-16 and 1931-37. There is also material relating to Runciman's attempt to solve the 1938 Sudeten crisis through his mission to Czechoslovakia.The collection also includes the diaries and some correspondence of Walter's wife, Hilda Runciman, herself briefly an M.P. Hilda's diaries have been found to be of particular value to researchers, providing as they do an insight into the world and circles in which she and her husband moved, sometimes revealing insider knowledge about the current talk in London Society, a classic example being Hilda's remarks in her 1936 diary about the abdication crisis and the King's intentions. In addition, there are 114 volumes of press cuttings, plus material relating to Walter Runciman's father, the 1st Baron Runciman, as well as documents relating to Sir Walter Leslie Runciman (1900-1989).

The Robert Spence Watson Collection is a collection of 500 volumes on the subject of English literature, consisting largely of the publications of literary societies such as the Shakespeare Society, the Spenser Society, the Ballad Society and the Chaucer Society, presented to the Library in 1908 by Robert Spence Watson, who was also one of the founders of the Durham College of Physical Science, and President of Armstrong College.

Consists mainly of letters to Robert Spence Watson. Topics include, but are not limited to, British politics and the Liberal party, contemporary Europe, Armstrong College (later Newcastle University), the Peace Society, lectures at the Literary and Philosophical Society of Newcastle upon Tyne, and contemporary literary and scientific achievements. Other regular recipients of letters include Elizabeth Spence Watson, Frederick Weiss, and Charles Prestwich Scott.

The Spence Watson's wide-ranging public activism, make their correspondence a valuable source of opinions on the social and political matters of the day from a wide range of prominent persons.

The Nicholson Collection comprises periodicals (newspapers, magazines and magazine supplements) and a small number of letters, postcards, pamphlets and photographs, relating to Spain, Ethiopia, Britain, and Italy. These are political and religious publications, for the most part, but include national and local newspapers, roughly covering the period of the late 1930s to the mid 1960s. Also included are The Workers Chronicle from May 1926 (covering the General Strike) and two U.S. Information Service documents from 1946.

Consists of published and unpublished material covering Sir Liam's professional career and achievements as;

Regional Medical Officer, Regional General Manager and Regional Director of Public Health for the Northern Regional Health Authority (1986 - 1994);

Regional General Manager, Regional Director and Regional Director of Public Health for the Northern and Yorkshire Regional Health Authority and NHS Executive: Northern and Yorkshire (1994 -1998);

Chief Medical Officer for England, Department of Health (1998 - 2010).

The majority of material relates to his time as Chief Medical Officer, covering his major health and health care campaigns, including published reports and contextual material related to these reports.

Also includes photographs, papers, correspondence and other material relating to Sir Liam's personal life, awards and honours.

Consists of 42 prints made from James Gillray's original engravings and documents relating to Newcastle University's acquisition of the prints.

With three early twentieth century exceptions, the Indian Tracts is a collection of nineteenth century pamphlets on a range of Indian subjects, such as local self-government, the Indian Civil Service, education, politics, economics, transport, the trade of opium, religion and war.

The collection consists of Herbert Loebl's business and personal records.

The business records contain group papers, sales and marketing files, finance files and general correspondence files for the following engineering and knowledge transfer enterprises with which Herbert Loebl was involved in his lifetime:

The collection also contains a number of annotated scrapbooks which trace the history of Loebl's engineering enterprises through photographs, newspaper cuttings and other ephemera.

Herbert Loebl's academic collection contains his early student notebooks from his degree studies in Electrical Engineering, and notes and source material for his subsequent doctoral thesis and Jewish history research. The collection also includes his certificates and various degree ceremony photographs.

Herbert Loebl received various awards during his lifetime and his personal collection includes photographs, newspaper clippings, scrapbooks, and letters of congratulations regarding his many honours.

The Grey Tracts reflect the interests of their former owner, the 2nd Earl Grey (1764-1845) whose Whig government was responsible for the 1832 Reform Act, 1833 Factory Act and the 1834 Poor Law Amendment Act. The pamphlets cover a broad range of historical, social and economic subjects including colonial policy, public finance and banking, the Corn Laws and agriculture, poor relief, slavery, Catholicism, Ireland and the Greek Revolution.