This is a collection of chiefly historical medical texts, numbering about 450 volumes, along with some archival material which was formerly owned by the neurologist and medical historian, Edwin Clarke (1919-1996). The collection usefully complements the Pybus and the Medical Collections.

Highlights include An inquiry concerning the history of the cowpox: principally with a view to supersede and extinguish the smallpox (1798) by George Pearson, the well-known physician, chemist and early advocate of Jenner's cowpox vaccination; and the Report from the Committee appointed to examine the physicians who have attended His Majesty, during his illness: touching the present state of His Majesty's health (1789), issued by Parliament during the period of King George III's recurrent mental illness. The collection also contains some modern secondary texts on various aspects of the history of medicine.

This collection represents the historical portion of the Library of Appleby Grammar School in Cumbria (formerly in the old county of Westmorland) and has been deposited on indefinite loan. The nucleus of the collection was the personal library of an early headmaster of the school, Reginald Bainbrigg [1545-1612?].Books in this collection range in publication date from the Fifteenth Century to the Twentieth Century. The collection can be searched on the library's catalogue and there is also a printed catalogue by the late Edgar Hinchcliffe, formerly a master at the school, available from the Special Collections reading room.The collection contains predominantly classical, theological, literary and historical works, as well as a number of early sixteenth-century English bindings. There are many sixteenth-century editions of works by classical authors, such as Cicero, while other highlights include several works by the English philosopher and enlightenment thinker John Locke and a 1561 Basel imprint of Martin Luther's Quaestionum Sacrarum.

The Bradshaw Collection contains books published 1601-1700 and is notable for its English Revolution, or Civil War, tracts, of which there are about sixty mostly describing local events, such as The Taking of Gateshead Hill: and blocking up of Newcastle … (1644), A Terrible and bloudy fight at Tinmouth Castle on Fryday last … (1648) and The King's declaration at Newcastle concerning his refusall to come to the parliament of England … (1647). Some of these are illustrated, often with wood-cut portraits.Other subjects represented in the collection include theology and some literature. Classical works, in Latin and Greek, by such authors as Catullus, Pliny, Virgil and Juvenal; Aristophanes, Dionysius and Euripides make up a large portion of the collection. The collection also has volume I of Edmund Gibson's English translation of William Camden's Britannia (1695), the first (Latin) edition of which had been the first comprehensive study of Britain.

Part of a bequest from Edwin Clarke (1919-1996), the Clarke Local Collection is more than a local history collection as it is quite strong in the literature of the region too: T. Wilson's The pitman's pay: and other poems (1843), Robert White's The Tynemouth nun: a poem (1829), Rhymes of Northern bards (1812) and more, as well as memoirs, sermons, topographical descriptions, guides and histories.

Although it comprises books published in the mid- to late-Twentieth Century, for the most part, it does contain a significant amount of more historic material, such as The papers which passed at New-castle betwixt his sacred Majestie and Mr Al. Henderson … (1649), R. Gardiner's Englands grievance discovered … (1655), A sentimental tour through Newcastle (1794), History of the water supply of Newcastle-upon-Tyne (1851) and several nineteenth-century directories and poll books.

The Burman-Alnwick Collection was brought together by Dr. C.C. Burman and presented to Alnwick U.D.C. by his son, Joseph Burman, to later be deposited in the Library on long-term loan.It consists of books, pamphlets, broadsides and other material printed in Alnwick 1700-1917 and is chiefly a local history collection, containing such items as An address to 'the four and twenty' of the borough of Alnwick: on certain improvements in the plan of education, pursued in the borough school [1839], The Alnwick Mercury, Northumberland Advertiser, and entertaining miscellany (1854-1859), The Journal of the Northumberland Agricultural Society (1850) and the Alnwick Mechanics' Institute's Annual Report [18--]. It is also something of a literary collection, containing Alnwick printings of well-known tales such as The babes in the wood [18--] and The ballad of Chevy Chase (1800) as well as children's literature and educational tools like The child's battledore [c.1830], works by James Beattie and Thomas Percy and various chapbooks and ballads. Published sermons and letters also appear.

Bequeathed by Edwin Clarke (1919-1996), approximately half of the Clarke Miscellaneous Collection was published in the Twentieth Century but the collection contains material dating back to 1655. It is a collection with a strong bias towards the occult, ritual and folklore, with some rogue items relating to book history.

Examples include A laconic narrative on the life & death of James Wilson, known by the name of Daft Jamie (1881) - a victim of Burke and Hare -, F. Hutchinson's An historical essay concerning witchcraft (1718), The Yorkshire spiritual telegraph and British harmonial advocate (1857) and a book on exercise by H. Halsted called Motion-life: or the demon of the age and means of its exorcism (1856).

The Cowen Tracts are almost two thousand pamphlets which were formerly owned by local (radical) M.P., Joseph Cowen (1829-1900). The tracts date mostly from the mid- to late-Nineteenth Century and reflect Cowen's interest in the social, educational, political and economic issues of the day.

There is some earlier material, such as Deed of incorporation for the insurance of ships printed by T. Angus, St. Nicholas' Church-Yard, Newcastle (1778). Pamphlets were an effective form of public debate because they could be circulated to a wider audience than books and authors could remain anonymous. The Cowen Tracts discuss Irish politics, foreign policy, women's rights, religion, education and public health and include such titles as The Union programme for 1880: constructive, not destructive, Irish legislation [1879?], Are women fit for politics?: are politics fit for women [185-] and The education of the agricultural labourer: a paper read before the Morpeth Chamber of Agriculture, on Wednesday, Feb. 2, 1870 by M.W. Ridley (1870).

The Grey Tracts reflect the interests of their former owner, the 2nd Earl Grey (1764-1845) whose Whig government was responsible for the 1832 Reform Act, 1833 Factory Act and the 1834 Poor Law Amendment Act. The pamphlets cover a broad range of historical, social and economic subjects including colonial policy, public finance and banking, the Corn Laws and agriculture, poor relief, slavery, Catholicism, Ireland and the Greek Revolution.