The White Collection, named after Robert White (1802-1874) was presented to King's College (now Newcastle University) by his great nephew George White Pickering. It is a rich source of literature as well as being strong in ecclesiastical and local history such as James Raine's writings on local history and antiquities.

There are works by John Dryden, William Hazlitt, Thomas Hood, James Thomson, Robert Burns, Mark Akenside, Thomas Chatterton, John Gay, H.W. Longfellow, Matthew Prior, John Keats, John Milton, James Hogg, John Clare, Edgar Allan Poe, George Herbert, William Cowper, Thomas Gray and the poems of Ossian as well as several works by S.T. Coleridge, including Aids to reflection (1848), Biographia literaria (1817), Confessions of an inquiring spirit (1849) and The friend (1850). Alongside the work of these distinguished authors sit English and Scottish ballads, garlands and chapbooks including some which were printed in Newcastle.

The Robert Spence Watson Collection is a collection of 500 volumes on the subject of English literature, consisting largely of the publications of literary societies such as the Shakespeare Society, the Spenser Society, the Ballad Society and the Chaucer Society, presented to the Library in 1908 by Robert Spence Watson, who was also one of the founders of the Durham College of Physical Science, and President of Armstrong College.

The Pybus Collection, originally brought together by the esteemed local medic and surgeon Professor Frederick Charles Pybus (1883-1975), is rich in material relating to the history of medicine. The collection consists chiefly of some 2000 volumes which are mostly classics of the history of medicine, with particular reference to anatomy, surgery and medical illustration.

Highlights are Gilles de Corbeil's De Pulsibus (1494), the first printed book on the pulse, as well as a 1648 edition of William Harvey's celebrated work Exercitatio anatomica de motu cordis et sanguinis in which he published his discoveries about the motion of the heart and blood. There is also a 1555 edition of one of the most important and influential books in the history of medicine, De Humani Corporis Fabrica by Andreas Versalius. Most of the other celebrated anatomists are represented here too, as well as later pioneers and experts.

The Pybus collection also includes engravings, portraits, busts, holographic letters and a set of bleeding bowls (currently housed at the Walton Library).

The Napoleon Collection contains books written in French as well as English language materials, published in the Twentieth Century with the exception of three nineteenth-century items. The books relate to Napoleon (1769-1821), the Napoleonic Wars and to the French empire and include 'notes and reminiscences' as well as histories.

This is a collection of over 2000 volumes and hundreds of pamphlets, covering the history of medicine and a broad range of medical subjects. The collection is rich in seventeenth, eighteenth and nineteenth-century works.

It includes books from the medical library of noted South Shields doctor T.M. Winterbottom (1766-1859), and highlights include Erasmus Darwin's Zoonomia (1794), John Abercrombie's Pathological and Practical Researches on Diseases of the Brain and Spinal Cord (1828), considered to have been the first textbook on Neuropathology, and several works by the famed botanist, humanist and physician Herman Boerhaave (1668-1738).

With three early twentieth century exceptions, the Indian Tracts is a collection of nineteenth century pamphlets on a range of Indian subjects, such as local self-government, the Indian Civil Service, education, politics, economics, transport, the trade of opium, religion and war.

The Grey Tracts reflect the interests of their former owner, the 2nd Earl Grey (1764-1845) whose Whig government was responsible for the 1832 Reform Act, 1833 Factory Act and the 1834 Poor Law Amendment Act. The pamphlets cover a broad range of historical, social and economic subjects including colonial policy, public finance and banking, the Corn Laws and agriculture, poor relief, slavery, Catholicism, Ireland and the Greek Revolution.

The Cowen Tracts are almost two thousand pamphlets which were formerly owned by local (radical) M.P., Joseph Cowen (1829-1900). The tracts date mostly from the mid- to late-Nineteenth Century and reflect Cowen's interest in the social, educational, political and economic issues of the day.

There is some earlier material, such as Deed of incorporation for the insurance of ships printed by T. Angus, St. Nicholas' Church-Yard, Newcastle (1778). Pamphlets were an effective form of public debate because they could be circulated to a wider audience than books and authors could remain anonymous. The Cowen Tracts discuss Irish politics, foreign policy, women's rights, religion, education and public health and include such titles as The Union programme for 1880: constructive, not destructive, Irish legislation [1879?], Are women fit for politics?: are politics fit for women [185-] and The education of the agricultural labourer: a paper read before the Morpeth Chamber of Agriculture, on Wednesday, Feb. 2, 1870 by M.W. Ridley (1870).