Conisists of 30 minute panel discussion programme presented by Andrew Marr, featuring Sir Liam, novelist William Boyd, broadcaster John Micklethwait, and journalist Polly Toynbee. Each offers predictions for the coming years; Sir Liam's being the inevitably of another influenza pandemic. Discusses historical trends, the need for good planning to mitigate harm, public and political reactions to pandemics, and what the UK is doing to prepare.

Other health issues discussed include stem cell research, Sir Liam's perception of the strengths and weaknesses of the NHS and reforms during his time as Chief Medical Officer, and the 'Nanny State' in relation to healthy lifestyles.

Consists of 56 powerpoint presentations, including notes, used by Sir Liam during speeches and presentations given during his time as Chief Medical Officer regarding his Special Reports, campaigns and other areas of work. Topics include organ and tissue retention , Annual Reports, Expert Medical Witnesses in Family Law Cases, outbreaks of foot and mouth disease (Aphtae epizooticae), the MMR vaccine, pandemic influenza outbreaks (including the H1N1 'Swine Flu'), and stem cell research.