This is a collection of over 2000 volumes and hundreds of pamphlets, covering the history of medicine and a broad range of medical subjects. The collection is rich in seventeenth, eighteenth and nineteenth-century works.

It includes books from the medical library of noted South Shields doctor T.M. Winterbottom (1766-1859), and highlights include Erasmus Darwin's Zoonomia (1794), John Abercrombie's Pathological and Practical Researches on Diseases of the Brain and Spinal Cord (1828), considered to have been the first textbook on Neuropathology, and several works by the famed botanist, humanist and physician Herman Boerhaave (1668-1738).